Indexing1COOKEY SN, 2BRIGGS FK
1,2Department of Internal Medicine; Rivers State University Teaching Hospital
DOI : https://doi.org/10.47191/ijmra/v8-i04-28Google Scholar Download Pdf
ABSTRACT:
Alcohol consumption is a recognized risk factor for cardiovascular diseases, including hypertension. However, its specific effects on carotid vessels have not been extensively studied. Understanding these effects is crucial for gaining insights into the pathogenesis of cardiovascular diseases, particularly in regions with high alcohol consumption like Nigeria. Methods A cross-sectional study, conducted in Rumuekini, Nigeria, involving forty-seven male (mean age 34.49 ± 17.25 years). Participants were categorized into mild, moderate, and excessive drinkers of alcohol. Data on blood pressures, body mass index, and carotid artery parameters were collected. Statistical analysis was performed to compare these parameters between alcohol consumers and data from control group of non-consumers. Results The mean SBP and DBP for alcohol consumers were 128.10 ± 21.92 mmHg and 77.20 ± 14.87 mmHg. The average daily alcohol consumption was 74.24 ± 43.34 g/day. BMI was significantly lower in alcohol consumers (23.46 ± 2.82 kg/m²) compared to nonconsumers (p=0.014). Right carotid diameter was also significantly smaller in alcohol consumers (p=0.027). The analysis indicated that even mild alcohol consumption was associated with elevated blood pressure. Additionally, BMI across all alcohol consumption levels fell within the overweight range, highlighting potential weight-related health issues. Conclusion Excessive Alcohol consumption, is associated with elevated blood pressures and increased cardiovascular risks. Alcohol consumers exhibit a smaller right carotid diameter, indicating potential vascular narrowing. These changes suggest that alcohol impacts blood vessels differently from non-consumers, contributing to increased risk of atherosclerosis and cardiovascular diseases, highlighting the need for targeted public health interventions.
KEYWORDS:Alcohol consumption, Cardiovascular diseases (CVDs), Hypertension, Carotid vessels, Carotid intima-media thickness (cIMT), Atherosclerosis.
REFERENCES1) GBD 2016 Alcohol Collaborators. Alcohol use and burden for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. The Lancet. 2018;392(10152):1015-35. doi: 10.1016/S0140-6736(18)31310-2.
2) Institute for Health Metrics and Evaluation (IHME). Global Burden of Disease Study 2016 (GBD 2016) Data Resources. Available from: https://ghdx.healthdata.org/gbd-2016.
3) Kadell M, et al. Alcohol use and burden for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. LSE Research Online. 2018. Available from: http://eprints.lse.ac.uk/90423/.
4) World Health Organization (WHO). Global status report on alcohol and health. Geneva: WHO; 2020. Available from: https://www.who.int/publications/i/item/9789240012047.
5) Zyriax S, Lau K, Kla ̈hn T, Boeing H, Vo ̈lzke H, Windler E. Association between alcohol consumption and carotid intima–media thickness in a healthy population: data of the STRATEGY study (Stress, Atherosclerosis and ECG Study). Eur J Clin Nutr. 2010;64(8):1199-1206. doi: 10.1038/ejcn.2010.144.
6) Kiechl S, Willeit J, Egger G, Oberhollenzer M, Aichner F. Alcohol consumption and carotid atherosclerosis: evidence of dosedependent atherogenic and antiatherogenic effects. Results from the Bruneck Study. Stroke. 1994;25(8):1593-8. doi: 10.1161/01.str.25.8.1593.
7) Zureik M, et al. Cross-sectional association between alcohol intake and carotid atherosclerosis in an elderly French population. J Hypertens. 2002;20(11):2193-200. doi: 10.1097/00004872-200211000-00014.
8) Lee Y-H, Shin M-H, Kweon S-S, Choi S-W, Kim H-Y, Ryu S-Y, et al. Alcohol consumption and carotid artery structure in Korean adults aged 50 years and older. BMC Public Health. 2009;9:358. doi: 10.1186/1471-2458-9-358
9) Ross R. Atherosclerosis—an inflammatory disease. N Engl J Med. 1999;340(2):115-26. doi: 10.1056/NEJM199901143400207.
10) Gimbrone MA Jr, Garcia-Cardena G. Endothelial cell dysfunction and the pathobiology of atherosclerosis. Circ Res. 2016;118(4):620-36. doi: .1161/CIRCRESAHA.115.306301.
11) Stein JH, Korcarz CE, Hurst RT, et al. Use of carotid ultrasound to identify subclinical vascular disease and evaluate cardiovascular disease risk: a consensus statement from the American Society of Echocardiography Carotid Intima-Media Thickness Task Force. J Am Soc Echocardiogr. 2008;21(2):93-111. doi: 10.1016/j.echo.2007.11.011.
12) Sample Size and the Central Limit Theorem. In: Research Methods. Washington DC: Statistical Consulting; 2021. Available from: https://www.statisticalconsulting.com/research-methods/sample-size-and-clt
13) Cookey SN, Martyns-Yellowe TB, Nyeche EO. Normal Extracranial Carotid Artery Parameters for A Healthy Nigerian Population. IOSR Journal of Dental and Medical Sciences. 2022;21(2):9-23. DOI: 10.9790/0853-2102110923.
14) Braunwald E, Diseases of the heart, Harrison principles of internal medicine, 15th edition. McGraw Hill Companies,1309 – 1355.
15) Obio-Akpor, https://en.wikipedia.org/wiki/Obio-Akpor [accessed on 27/02/2022] The Impact of Alcohol on The Carotid Parameters: In Rumosi Residents IJMRA, Volume 8 Issue 04 April 2025 www.ijmra.in Page 1745
16) Diana Dinescu, University of Virginiahttps://news.virginia.edu/content/does-marriage-affect-drinking-new-study-providesinsights
17) Ellison, Chri Ellison, Christopher G., et al. “Gender, Marital Status, and Alcohol Behavior: The Neglected Role of Religion.” Journal for the Scientific Study of Religion, vol. 47, no. 4, [Society for the Scientific Study of Religion, Wiley], 2008, pp. 660–77, http://www.jstor.org/stable/20486961
Volume 08 Issue 04 April 2025
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