1,2Zhongguo Huang, MPH, 1,2Tao Liu, PhD, 3Yan Shi, PhD, 3Yanfei Guo, PhD, 1,2Guanhao He PhD, 1,2JianXiong Hu, PhD, 1,2Xiaomei Dong, PhD, 5Jianpeng Xiao, PhD, 1,2Ziqiang Lin, PhD, 6Fan Wu, PhD,1,2 Wenjun Ma, PhD.
1Department of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou, 510632, China
2China Greater Bay Area Research Center of Environmental Health, School of Medicine, Jinan University, Guangzhou, 510632, China
3Shanghai Municipal Centre for Disease Control and Prevention, Shanghai, 200336, China
4Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, 511430, China
5Shanghai Medical College, Fudan University, Shanghai, 200032, China
6Shanghai Medical College, Fudan University, 130 Dong-An Road, Xuhui District, Shanghai
Corresponding Authors: Fan Wu, Wenjun Ma
DOI : https://doi.org/10.47191/ijmra/v7-i05-64Google Scholar Download Pdf
ABSTRACT:
Background: Few previous stud ies ha ve examined the joint effect of long term exposure to temperature and relative humidity ( RH on ast hma This study endeavors t o explore the combined association between long term co exposure to temperature and R H and asthma in China.
Methods: The individual data of asthma were collected from the wave 1 to wave 3 (2007 2019) of the Study on global AGEing and adult health in China. M eteorological factors data were obtained from the European Center for Medium range Weather Forecasts Reanalysis 5 (ERA5) and extracted from the corresponding interpolated grid according to individual residential latitude, longi tude and survey time. Individual and joint association of long term exposure to annual mean temperature and RH with asthma were estimated using Cox regression model and Quantile Based g Computation model Q gcomp)gcomp), respectively Then , the joint effects of different temperature RH compound events w ere further estimated
Results: We observed negative association between both temperature and RH with asthma. In individual effect analysis, for 1 °C or 1% decrease in 3 year average temperature and RH , asthma increased 4 44 (95% 1 76 7 0 5) and 6 45 (95% 2 79 9 98 respectively. The joint effect of long term exposure to temperature and RH on asthma was also negative . F or each percentile decreasing of both temperature and RH asthma decreased 1.50% (95%CI: 0.85% 2.15%) in total population . People 60 years old and female were more susceptible to mixture exposure to low temperature and low RH. W e also observed a higher risk of asthma in dry cold event ( 2.44 , 95%CI: 1 67 3 55 than wet cold, wet hot and dry hot events
Conclusion: Long term exposure to t emperature and RH may jointly associate with asthma , and low RH and cold may have higher risk on asthma onset .
KEYWORDS:A sthma; Temperature; RH Quantile Based g Computation model , J oint effect
REFERENCES1) World Health Organization. Asthma Key Fact.: World Health Organization; 2022 [15 Feb 2023]; Available from: https://www.who.int/en/news-room/fact-sheets/detail/asthma.
2) Institute for Health Metrics and Evaluation. GBD Result. Institute for Health Metrics and Evaluation; 2019 [15 Feb 2023]; Available from: https://vizhub.healthdata.org/gbd-results/.
3) Liu M, Gan H, Lin Y, Lin R, Xue M, Zhang T, et al. Prevalence and Disability-Adjusted Life Year Rates of Asthma in China: Findings from the GBD Study 2019 of the G20. Int J Environ Res Public Health. 2022 Nov 8;19(22). PMID: 36429381. doi: 10.3390/ijerph192214663.
4) Huang K, Yang T, Xu J, Yang L, Zhao J, Zhang X, et al. Prevalence, risk factors, and management of asthma in China: a national cross-sectional study. Lancet. 2019 Aug 3;394(10196):407-18. PMID: 31230828. doi: 10.1016/s0140-6736(19)31147-x.
5) Abe T, Tokuda Y, Ohde S, Ishimatsu S, Nakamura T, Birrer RB. The relationship of short-term air pollution and weather to ED visits for asthma in Japan. The American Journal of Emergency Medicine. 2009 2009/02/01/;27(2):153-9. doi: https://doi.org/10.1016/j.ajem.2008.01.013.
6) Hashimoto M, Fukuda T, Shimizu T, Watanabe S, Watanuki S, Eto Y, et al. Influence of climate factors on emergency visits for childhood asthma attack. Pediatr Int. 2004 Feb;46(1):48-52. PMID: 15043664. doi: 10.1111/j.1442-200X.2004.01835.x.
7) Garty BZ, Kosman E, Ganor E, Berger V, Garty L, Wietzen T, et al. Emergency room visits of asthmatic children, relation to air pollution, weather, and airborne allergens. Ann Allergy Asthma Immunol. 1998;81(6):563-70. doi: 10.1016/S1081-1206(10)62707-X.
8) Strauss RH, McFadden ER, Ingram RH, Jaeger JJ, Stearns DR. Enhancement of Exercise-Induced Asthma by Cold Air. New England Journal of Medicine. 1977;297(14):743-7. PMID: 895804. doi: 10.1056/nejm197710062971402.
9) Lam HCY, Hajat S, Chan EYY, Goggins WB. Different sensitivities to ambient temperature between first- and re-admission childhood asthma cases in Hong Kong – A time series study. Environmental Research. 2019 2019/03/01/;170:487-92. doi: https://doi.org/10.1016/j.envres.2018.12.002.
10) Xu Z, Crooks JL, Davies JM, Khan AF, Hu W, Tong S. The association between ambient temperature and childhood asthma: a systematic review. International Journal of Biometeorology. 2018 2018/03/01;62(3):471-81. doi: 10.1007/s00484-017-1455-5.
11) Cong X, Xu X, Zhang Y, Wang Q, Xu L, Huo X. Temperature drop and the risk of asthma: a systematic review and meta-analysis. Environmental Science and Pollution Research. 2017 2017/10/01;24(28):22535-46. doi: 10.1007/s11356-017-9914-4.
12) Deng R, Ma P, Li B, Wu Y, Yang X. Development of allergic asthma and changes of intestinal microbiota in mice under high humidity and/or carbon black nanoparticles. Ecotoxicology and Environmental Safety. 2022 2022/08/01/;241:113786. doi: https://doi.org/10.1016/j.ecoenv.2022.113786.
13) Wang M, Deng R. Effects of carbon black nanoparticles and high humidity on the lung metabolome in Balb/c mice with established allergic asthma. Environmental Science and Pollution Research. 2022 2022/09/01;29(43):65100-11. doi: 10.1007/s11356-022-20349-0.
14) Lam HC-y, Li AM, Chan EY-y, Goggins WB. The short-term association between asthma hospitalisations, ambient temperature, other meteorological factors and air pollutants in Hong Kong: a time-series study. Thorax. 2016;71(12):1097-109. doi: 10.1136/thoraxjnl-2015-208054.
15) Zhang Y, Dong T, Hu W, Wang X, Xu B, Lin Z, et al. Association between exposure to a mixture of phenols, pesticides, and phthalates and obesity: Comparison of three statistical models. Environment International. 2019 2019/02/01/;123:325-36. doi: https://doi.org/10.1016/j.envint.2018.11.076.
16) Yu G, Jin M, Huang Y, Aimuzi R, Zheng T, Nian M, et al. Environmental exposure to perfluoroalkyl substances in early pregnancy, maternal glucose homeostasis and the risk of gestational diabetes: A prospective cohort study. Environment International. 2021 2021/11/01/;156:106621. doi: https://doi.org/10.1016/j.envint.2021.106621.
17) Gennings C, Curtin P, Bello G, Wright R, Arora M, Austin C. Lagged WQS regression for mixtures with many components. Environ Res. 2020 Jul;186:109529. PMID: 32371274. doi: 10.1016/j.envres.2020.109529.
18) Chen L, Sun Q, Peng S, Tan T, Mei G, Chen H, et al. Associations of blood and urinary heavy metals with rheumatoid arthritis risk among adults in NHANES, 1999–2018. Chemosphere. 2022 2022/02/01/;289:133147. doi: https://doi.org/10.1016/j.chemosphere.2021.133147.
19) Keil AP, Buckley JP, O'Brien KM, Ferguson KK, Zhao S, White AJ. A Quantile-Based g-Computation Approach to Addressing the Effects of Exposure Mixtures. Environ Health Perspect. 2020 Apr;128(4):47004. PMID: 32255670. doi: 10.1289/ehp5838.
20) Kowal P, Chatterji S, Naidoo N, Biritwum R, Fan W, Lopez Ridaura R, et al. Data resource profile: the World Health Organization Study on global AGEing and adult health (SAGE). Int J Epidemiol. 2012 Dec;41(6):1639-49. PMID: 23283715. doi: 10.1093/ije/dys210.
21) Luo M, Ding D, Bauman A, Negin J, Phongsavan P. Social engagement pattern, health behaviors and subjective well-being of older adults: an international perspective using WHO-SAGE survey data. BMC Public Health. 2020 Jan 23;20(1):99. PMID: 31973695. doi: 10.1186/s12889-019-7841-7.
22) Kailembo A, Preet R, Stewart Williams J. Common risk factors and edentulism in adults, aged 50 years and over, in China, Ghana, India and South Africa: results from the WHO Study on global AGEing and adult health (SAGE). BMC Oral Health. 2016 Jul 27;17(1):29. PMID: 27465011. doi: 10.1186/s12903-016-0256-2.
23) Shin S, Bai L, Burnett RT, Kwong JC, Hystad P, van Donkelaar A, et al. Air Pollution as a Risk Factor for Incident Chronic Obstructive Pulmonary Disease and Asthma. A 15-Year Population-based Cohort Study. Am J Respir Crit Care Med. 2021 May 1;203(9):1138-48. PMID: 33147059. doi: 10.1164/rccm.201909-1744OC.
24) Oses N, Azpiroz I, Marchi S, Guidotti D, Quartulli M, I GO. Analysis of Copernicus' ERA5 Climate Reanalysis Data as a Replacement for Weather Station Temperature Measurements in Machine Learning Models for Olive Phenology Phase Prediction. Sensors (Basel). 2020 Nov 9;20(21). PMID: 33182272. doi: 10.3390/s20216381.
25) European Center for Medium-range Weather Forecasts. ERA5-Land hourly data from 1950 to present. ECMWF; 2019 [February 26, 2023]; Available from: https://cds.climate.copernicus.eu/cdsapp#!/dataset/10.24381/cds.e2161bac?tab=overview.
26) Yilmaz M. Accuracy assessment of temperature trends from ERA5 and ERA5-Land. Science of The Total Environment. 2023 2023/01/15/;856:159182. doi: https://doi.org/10.1016/j.scitotenv.2022.159182.
27) Aheto JMK, Udofia EA, Kallson E, Mensah G, Nadia M, Nirmala N, et al. Prevalence, socio-demographic and environmental determinants of asthma in 4621 Ghanaian adults: Evidence from Wave 2 of the World Health Organization's study on global AGEing and adult health. PLoS One. 2020;15(12):e0243642. PMID: 33296442. doi: 10.1371/journal.pone.0243642.
28) Ren M, Wang Q, Zhao W, Ren Z, Zhang H, Jalaludin B, et al. Effects of extreme temperature on the risk of preterm birth in China: A population-based multi-center cohort study. Lancet Reg Health West Pac. 2022 Jul;24:100496. PMID: 35899090. doi: 10.1016/j.lanwpc.2022.100496.
29) Zhang Z, Reinikainen J, Adeleke KA, Pieterse ME, Groothuis-Oudshoorn CGM. Time-varying covariates and coefficients in Cox regression models. Ann Transl Med. 2018 Apr;6(7):121. PMID: 29955581. doi: 10.21037/atm.2018.02.12.
30) Li G, Liu J, Lu H, Hu W, Hu M, He J, et al. Multiple environmental exposures and obesity in eastern China: An individual exposure evaluation model. Chemosphere. 2022 2022/07/01/;298:134316. doi: https://doi.org/10.1016/j.chemosphere.2022.134316.
31) Letellier N, Zamora S, Yang JA, Sears DD, Jankowska MM, Benmarhnia T. How do environmental characteristics jointly contribute to cardiometabolic health? A quantile g-computation mixture analysis. Prev Med Rep. 2022 Dec;30:102005. PMID: 36245803. doi: 10.1016/j.pmedr.2022.102005.
32) Snowden JM, Rose S, Mortimer KM. Implementation of G-computation on a simulated data set: demonstration of a causal inference technique. Am J Epidemiol. 2011 Apr 1;173(7):731-8. PMID: 21415029. doi: 10.1093/aje/kwq472.
33) Hu Y, Zhang Z, Hua B, Tao L, Chen W, Gao Y, et al. The interaction of temperature and relative humidity affects the main aromatic components in postharvest Torreya grandis nuts. Food Chemistry. 2022 2022/01/30/;368:130836. doi: https://doi.org/10.1016/j.foodchem.2021.130836.
34) Lam HC, Li AM, Chan EY, Goggins WB, 3rd. The short-term association between asthma hospitalisations, ambient temperature, other meteorological factors and air pollutants in Hong Kong: a time-series study. Thorax. 2016 Dec;71(12):1097-109. PMID: 27343213. doi: 10.1136/thoraxjnl-2015-208054.
35) Son J-Y, Bell ML, Lee J-T. The impact of heat, cold, and heat waves on hospital admissions in eight cities in Korea. International Journal of Biometeorology. 2014 2014/11/01;58(9):1893-903. doi: 10.1007/s00484-014-0791-y.
36) Kaminsky DA BJ, Irvin CG. Effects of cool, dry air stimulation on peripheral lung mechanics in asthma. Am J Respir Crit Care Med. 2000;162(1):179-86. doi: 10.1164/ajrccm.162.1.9806079.
37) Yonghua S, Mehrabi Nasab E, Y. L. Effect of Temperature and Humidity on the Allegro-inflammatory Factors and Allergic Rhinitis-related Behavior. Iran J Allergy Asthma Immunol. 2022;21(6):704-710. doi: 10.18502/ijaai.v21i6.11531.
38) Puvvula J, Poole JA, Gonzalez S, Rogan EG, Gwon Y, Rorie AC, et al. Joint association between ambient air pollutant mixture and pediatric asthma exacerbations. Environ Epidemiol. 2022 Oct;6(5):e225. PMID: 36249268. doi: 10.1097/ee9.0000000000000225.
39) Liu T, Jiang Y, Hu J, Li Z, Li X, Xiao J, et al. Joint Associations of Short-Term Exposure to Ambient Air Pollutants with Hospital Admission of Ischemic Stroke. Epidemiology. 2023;34(2):282-292. doi: 10.1097/EDE.0000000000001581.
40) HO K. Cold air-provoked respiratory symptoms: the mechanisms and management. Int J Circumpolar Health. Int J Circumpolar Health. 2007 66(2):91-100. doi: 10.3402/ijch.v66i2.18237.
41) Sue-Chu M. Winter sports athletes: long-term effects of cold air exposure. British Journal of Sports Medicine. 2012;46(6):397-401. doi: 10.1136/bjsports-2011-090822.
42) Strauss RH, McFadden ER, Jr., Ingram RH, Jr., Deal EC, Jr., Jaeger JJ. Influence of heat and humidity on the airway obstruction induced by exercise in asthma. J Clin Invest. 1978 Feb;61(2):433-40. PMID: 621282. doi: 10.1172/jci108954.
43) Toskala E, Kennedy DW. Asthma risk factors. Int Forum Allergy Rhinol. 2015 Sep;5 Suppl 1(Suppl 1):S11-6. PMID: 26335830. doi: 10.1002/alr.21557.
45) Weilnhammer V, Schmid J, Mittermeier I, Schreiber F, Jiang L, Pastuhovic V, et al. Extreme weather events in europe and their health consequences - A systematic review. International journal of hygiene and environmental health. 2021 Apr;233:113688. PMID: 33530011. doi: 10.1016/j.ijheh.2021.113688.
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