1Lobna Abdalla Elfrgani, 2Ghazala Othman Ali Elfeitouri, 3Mona Adnan Elkhattib, 3Mona Moftah Alabbar, 3Salha Abdullah Alobidy, 3Sally Ali khalaf, 1Abeer H. Amer
1Histology Department, Faculty of Medicine, University of Benghazi
2Medicine Department, Faculty of Medicine, University of Benghazi
3Cytotechnology Department, Faculty of Biomedical sciences, University of Benghazi
DOI : https://doi.org/10.47191/ijmra/v7-i11-25Google Scholar Download Pdf
ABSTRACT:
Background:
Thyroid nodules constitute a common endocrine disorder, these nodules could be solitary, multiple, cystic, or solid. Increasing age, female gender, iodine deficiency, and history of thyroid radiation all are high risk for thyroid nodules. FNAC representing the most cost-effective diagnostic tool used in the assessment of nodules of the thyroid.
Objective of the study:
The aim of this study is to evaluate the result of fine needle aspiration cytology (FNAC) and assess thyroid status using of thyroid hormone obtained from patients with thyroid nodules.
Materials and methods:
this is a retrospective study, includes collection of data from available cases of thyroid nodules underwent fine needle aspiration between 2021 to 2023, data regarding age, sex, TFT, USS, FNAC was collected from the archive of endocrine out patients clinic of Benghazi Medical Center and from endocrine clinic of Benghazi diabetic center. The analysis was done using the SPSS program.
Result:
A total of 60 cases were studied, Data was collected from 60 patient’s files for years between 2021 and 2023. The mean age of the patients with FNAC selected for this study was 49.65, and ranged from 21-80 years. The gender distribution shows female predominance in which female cases were 53 (98.33%) while only one case (1.67%) was reported among men. The size of nodules in our cases range from 1cm to 4.5 cm. The mean size of nodules is 1.89cm. In this study the largest group of nodules located in right lobe (21) cases then left lobe (20) cases then both (17) cases and in isthmus only 2 cases. Most of the cases thyroid function test result shows an euthyroid status (38) cases. FNAC of thyroid nodule showed that most of patient’s result diagnosed as benign nodules (47) cases.
Conclusion:
FNAC is a key tool in diagnosis of thyroid nodule as it has safe, minimally invasive and cost effective diagnostic role.
REFERENCES
1) Haugen, B. R., Alexander, E. K., Bible, K. C., Doherty (2016). 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid : official journal of the American Thyroid Association, 26(1), 1–133.
2) Zamora EA, Khare S, Cassaro S. Thyroid Nodule. [Updated 2022 Sep 5]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-.
3) Yeung, M. J., & Serpell, J. W. (2008). Management of the solitary thyroid nodule. The oncologist, 13(2), 105–112.https://doi.org/10.1634/theoncologist.2007-0212
4) Dean DS, Gharib H. (2008) Epidemiology of thyroid nodules. Best Pract Res Clin Endocrinol Metab. 22(6):901-11.
5) Cohen A, Rovelli A, Merlo DF, van Lint MT, Lanino E, Bresters D, Ceppi M, Bocchini V, Tichelli A, Socié G. (2007). Risk for secondary thyroid carcinoma after hematopoietic stem-cell transplantation: an EBMT Late Effects Working Party Study. J Clin Oncol. 10;25(17):2449-54.
6) Welker MJ, Orlov D. (2003). Thyroid nodules. Am Fam Physician. 01;67(3):559-66.
7) Belfiore A, La Rosa GL, La Porta GA, Giuffrida D, Milazzo G, Lupo L, Regalbuto C, Vigneri R. 1992 Oct; Cancer risk in patients with cold thyroid nodules: relevance of iodine intake, sex, age, and multinodularity. Am J Med. 93(4):363-9.
8) Popoveniuc G, Jonklaas J. (2012) Thyroid nodules. Med Clin North Am ;96(2):329-49.
9) Elmatri, H. H., Gheryani, N. A., Saad, R. H. F. and Amer, A. H. A. (2024) Perioperative Diagnosis of Thyroid Lesions through Fine-Needle Aspiration: A Clinicopathological Retrospective Analysis. Libyan International Medical University Journal, 9 (1).
10) Bahaj, A. S., Alkaff, H. H., Melebari, B. N., Melebari, A. N., Sayed, S. I., Mujtaba, S. S., (2020). Role of fine-needle aspiration cytology in evaluating thyroid nodules. A retrospective study from a tertiary care center of Western region, Saudi Arabia. Saudi medical journal, 41(10), 1098–1103.
11) Abeer H. A. Amer, Amina B. M. Younis, Muftah S. El saeiti, Nabeia Gheryani (2022). Histological Characters of Thyroid Nodules in Patients that Underwent Thyroid Surgery in Endocrine Clinic at Alkeesh Polyclinic in Benghazi – Libya within the years 2014 - 2020. Benghazi University Medical Journal BUMJ 2 (2), 103-112,2022.
12) Park, J. H., Yoon, S. O., Son, E. J., Kim, H. M., Nahm, J. H., & Hong, S. (2014). Incidence and malignancy rates of diagnoses in the bethesda system for reporting thyroid aspiration cytology: an institutional experience. Korean journal of pathology, 48(2), 133–139.
13) Bchir, A., Bdioui, A., Zammel, H., Missaoui, N., Hmissa, S., & Mokni, M. (2021). The importance of using fine-needle aspiration cytology in the diagnosis of thyroid nodules. Annals of medicine and surgery (2012), 63, 102153.
14) Naz, S., Hashmi, A. A., Faridi, N., Edhi, M. M., Kamal, A., & Khan, M. (2014). Diagnostic accuracy of Bethesda system for reporting thyroid cytopathology: an institutional perspective. International archives of medicine, 7(1), 1-5.
15) Gupta, M., Gupta, S., & Gupta, V. B. (2010). Correlation of fine needle aspiration cytology with histopathology in the diagnosis of solitary thyroid nodule. Journal of thyroid research, 2010, 379051.
16) Bhat, S., Bhat, N., Bashir, H., Farooq, S., Reshi, R., Nazeir, M. J., & Niyaz, I. (2016). The bethesda system for reporting thyroid cytopathology: a two year institutional audit. International Journal of Current Research and Review, 8(6), 5.
17) Dhamecha, M. P., Swami, S. Y., & Valand, A. G. (2018). FNAC study of thyroid lesions using the Bethesda system. Trop J Path Micro, 4, 101-108.
18) Patel, K. A., Anandani, G., Sharma, B. S., & Parmar, R. A. (2023). Study of Fine Needle Aspiration Cytology (FNAC) of Thyroid Gland According to the Bethesda System. Cureus, 15(4), e37371.
19) Handa, U., Garg, S., Mohan, H., & Nagarkar, N. (2008). Role of fine needle aspiration cytology in diagnosis and-management of thyroid lesions: A study on 434 patients. Journal of cytology, 25(1), 13-17.
20) Cavallo, A., Johnson, D. N., White, M. G., Siddiqui, S., Antic, T., Mathew, M., Grogan, R. H., Angelos, P., Kaplan, E. L., & Cipriani, N. A. (2017). Thyroid Nodule Size at Ultrasound as a Predictor of Malignancy and Final Pathologic Size. Thyroid: official journal of the American Thyroid Association, 27(5), 641–650.
21) Al-Hakami, H. A., Alqahtani, R., Alahmadi, A., Almutairi, D., Algarni, M., & Alandejani, T. (2020). Thyroid Nodule Size and Prediction of Cancer: A Study at Tertiary Care Hospital in Saudi Arabia. Cureus, 12(3), e7478.
22) Jinih, M., Faisal, F., Abdalla, K., Majeed, M., Achakzai, A. A., Heffron, C., McCarthy, J., & Redmond, H. P. (2020). Association between thyroid nodule size and malignancy rate. Annals of the Royal College of Surgeons of England, 102(1), 43–48.
Volume 07 Issue 11 November 2024
There is an Open Access article, distributed under the term of the Creative Commons Attribution – Non Commercial 4.0 International (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/), which permits remixing, adapting and building upon the work for non-commercial use, provided the original work is properly cited.
Our Services and Policies
Authors should prepare their manuscripts according to the instructions given in the authors' guidelines. Manuscripts which do not conform to the format and style of the Journal may be returned to the authors for revision or rejected.
The Journal reserves the right to make any further formal changes and language corrections necessary in a manuscript accepted for publication so that it conforms to the formatting requirements of the Journal.
International Journal of Multidisciplinary Research and Analysis will publish 12 monthly online issues per year,IJMRA publishes articles as soon as the final copy-edited version is approved. IJMRA publishes articles and review papers of all subjects area.
Open access is a mechanism by which research outputs are distributed online, Hybrid open access journals, contain a mixture of open access articles and closed access articles.
International Journal of Multidisciplinary Research and Analysis initiate a call for research paper for Volume 07 Issue 11 (November 2024).
PUBLICATION DATES:
1) Last Date of Submission : 26 November 2024 .
2) Article published within a week.
3) Submit Article : editor@ijmra.in or Online
Why with us
1 : IJMRA only accepts original and high quality research and technical papers.
2 : Paper will publish immediately in current issue after registration.
3 : Authors can download their full papers at any time with digital certificate.
The Editors reserve the right to reject papers without sending them out for review.
Authors should prepare their manuscripts according to the instructions given in the authors' guidelines. Manuscripts which do not conform to the format and style of the Journal may be returned to the authors for revision or rejected. The Journal reserves the right to make any further formal changes and language corrections necessary in a manuscript accepted for publication so that it conforms to the formatting requirements of the Journal.