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VOLUME 04 ISSUE 11 NOVEMBER 2021

Age and Weight-Related Variation in Fasting Plasma Glucose among Inhabitants of Enugu Metropolis, Southeast Nigeria
1,2Ogbu, Innocent S. I.,2 Ikpeama Anthony I.,1 Ogbu, Chinemerem C.,
1 Nwobodo, Emmanuel I., 3Odochi, Ogbu C.,4 Nduka, Okeke J.
1Department of Medical Laboratory Science, Evangel University Akaeze. Ebonyi State. Nigeria
2Department of Medical Laboratory Science, University of Nigeria, Enugu Campus. Enugu Nigeria
3Department of Physiology, Evangel University Akaeze. Ebonyi State. Nigeria
4Department of Chemical Pathology, Faculty of Clinical Medicine. Ebonyi State University. Abakaliki. Ebonyi State. Nigeria
DOI : https://doi.org/10.47191/ijmra/v4-i11-16

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ABSTRACT:


Aim:
Fasting plasma glucose (FPG) is the concentration of plasma glucose after an overnight (≤ 8 hours) fast. It is diagnostic of diabetes mellitus and prediabetes. It is used in the screening of other health conditions and monitoring of treatment of diabetes. It is useful to determine factors that influence FPC for more accurate interpretation of the test.
Procedure:
One hundred and fifty (150) apparently healthy subjects aged 1 – 80 years were recruited for the study after an informed consent. Their ages were noted, weight and height measured and body mass index (BMI) calculated. Two milliliters of fasting blood sample were collected from each before 10 am each day and put into fluoride-oxalate bottle. The samples were spun and the plasma analyzed for glucose on the same day using the Glucose oxidase method.
Results:
The range of FPG values obtained was 2.3 – 7.0mmol/l and mean age, BMI, and FPG, (±SD), were 38.25 ±21.86 years, 26.49 ±6.37 and 4.23 ±0.96mmol/l respectively. FPG correlated with age (r 2 = 0.4469; p=0.0001) and BMI (r 2 =0.2271; p=0.0001). FPG differed with age and BMI. 98% of the subjects had FPG within the range 2.2 - 6.6 mmol/l with 72% falling within the range 3.4 – 5.5mmol/l. There was no significant difference between the male and female values though this existed in their BMI, (p=0.0178).
Conclusion:
FPG is influenced by both age and BMI of subjects, there is, therefore, the need to take these factors into consideration in the interpretation of results of FPG tests.

Keywords

Fasting plasma glucose; body weight; age; body mass index.

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VOLUME 04 ISSUE 11 NOVEMBER 2021

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