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Volume 07 Issue 08 August 2024

Frequency of Nutritional Megaloblastic Anemia among Students in Khartoum, Sudan
Tariq E. Elmissbah
Department of Clinical Laboratory Sciences, College of Applied Meical Sciences, Taif University, Taif, KSA
DOI : https://doi.org/10.47191/ijmra/v7-i08-56

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ABSTRACT:

Background: Megaloblastic anemia is a generative macrocytic anemia characterized by nuclear dysmaturity and the nucleus immature appearance in comparison to the cytoplasm due to a defect in DNA synthesis anemia is a rare ailment in children that is usually caused by a vitamin deficiency or gastrointestinal disorder

Objectives: The main objective of this study was to detect the frequency of nutritional megaloblastic anemia in male elementary-school children by measuring hemoglobin (Hb), red blood cell (RBC) count, hematocrit (HCT), and serum folate levels.

Methods: This study examined 300 male primary-school children in Khartoum, Sudan. A 2.5-ml of blood was drawn from each student and placed in an ethylene diamine tetra acetic acid (EDTA) vial to estimate the Hb level, RBC count, and HCT using an automated blood analyzer. Another 2.5 mL of blood were drawn from the same students into a plain container and examined for serum folate.

Results: The mean Hb was 12.7 g/dl (two standard deviations), the RBC count was 4.71012 cells/L, and the mean packed cell volume (PCV) was 37.2%, and the mean serum folate was 4.4 ng/L.

Conclusion: The blood parameters and serum folate were found to be within normal ranges. According to the findings, the nutritional status of the primary-school students was good, and megaloblastic anemia was not common. This type of research should be done on a frequent basis to assess children's nutritional health.

REFERENCES
1) Kaur N, Nair V, Sharma S, Dudeja P, Puri P. A descriptive study of clinico-hematological profile of megaloblastic anemia in a tertiary care hospital. Med J Armed Forces India 2018; 74(4): 365-370. doi:10.1016/j.mjafi.2017.11.005

2) Petry N, Nizamov F, Woodruff BA, Ishmakova R, Komilov J, Wegmüller R, et al. Risk Factors for Anemia and Micronutrient Deficiencies among Women of Reproductive Age-The Impact of the Wheat Flour Fortification Program in Uzbekistan. Nutrients 2020; 12(3): 714. doi: 10.3390/nu12030714. PMID: 32156021; PMCID: PMC7146397.

3) Al Rakaf MS, Kurdi AM, Ammari AN, Al Hashem AM, Shoukri MM, Garne E, et al. Patterns of folic acid use in pregnant Saudi women and prevalence of neural tube defects Results from a nested case-control study. Prev Med Rep 2015; 2: 572–6

4) Haidar J, Melaku U, Pobocik RS. Folate deficiency in women of reproductive age in nine administrative regions of Ethiopia: an emerging public health problem. South Afr J Clin Nutr 2010; 23(3): 132–7

5) Hasswane N, Bouziane A, Mrabet M, et al. Prevalence and factors associated with anemia pregnancy in a group of Moroccan pregnant women. J Biosci Med 2015; 3(10): 88–97

6) Abdullahi H, Gasim GI, Saeed A, Imam AM, Adam I. Antenatal iron and folic acid supplementation use by pregnant women in Khartoum, Sudan. BMC Res Notes 2014; 7(1): 498. doi: 10.1186/1756-0500-7-498

7) Ghaderi N, Ahmadpour M, Saniee N, Karimi F, Ghaderi C, Mirzaei H. Effect of education based on the Health Belief Model (HBM) on anemia preventive behaviors among Iranian girl students. Int J Pediatr 2017; 5(6): 5043–5052.

8) Rahman MM, Abe SK, Rahman MS, et al. Maternal anemia and risk of adverse birth and health outcomes in low-and middle-income countries: systematic review and meta-analysis. Am J Clin Nutr 2016; 103(2): 495–504. doi: 10.3945/ajcn.115.107896 .

9) Siddiqui B, Rabindranath D, Faridi SH, Khan AA, Haiyat S, Eswaran R. Megaloblastic anemia: A common but often neglected cause of pyrexia of unknown origin. J Transl Int Med 2015 Apr-Jun; 3(2): 64–67. PMID: 27847889

10) Maynard AG, Pohl NK, Mueller AP, Petrova B, et al. Folate depletion induces erythroid differentiation through perturbation of de novo purine synthesis. Sci Adv 2024 Feb 2; 10(5): eadj9479. doi: 10.1126/sciadv.adj9479

11) Rodrigues V, Dias A, Brito MJ, Galvão I, Ferreira GC. severe megaloblastic anaemia in an infant. BMJ Case Rep 2011; 2011: bcr0220113835. doi: 10.1136/bcr.02.2011.3835

12) Ridwan N, Shafi A. Adherence to iron folate supplementation and associated factors among pregnant women attending antenatal care at public hospitals in Jigjiga Town, Somali Region. Ethiopia 2020. Pan Afr Med J 2021; 40: 196. doi: 10.11604/pamj.2021.40.196.27958
Volume 07 Issue 08 August 2024

There is an Open Access article, distributed under the term of the Creative Commons Attribution – Non Commercial 4.0 International (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/), which permits remixing, adapting and building upon the work for non-commercial use, provided the original work is properly cited.


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