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  • ISSN[Online] : 2643-9875  ||  ISSN[Print] : 2643-9840

VOLUME 03 ISSUE 10 OCTOBER 2020

Probable Human Bocavirus meningitisin a child
1Dr. Badar Al-Dhouyani,2 Dr.Saniya Al Husaini, 3Dr.Suod Al Shabibi, 4Dr.Nawal Al-Kindi, 5Dr.Amal Al Maani.
DOI : https://doi.org/10.47191/ijmra/v3-i10-02

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ABSTRACT:

Human bocavirus (HBoV; family Parvoviridae; genus Bocavirus) was discovered in 2005 and was distributed worldwide (1). HBoV has gained considerable clinical relevance since its discovery. It has been detected in respiratory specimens, and when it causes disease, it seems to have a broad spectrum of signs and symptoms. Our patient was a five years old girl admitted to the Royal Hospital in Oman, on March 2019. Presented with headache, vomiting, fever, phonophobia and significant irritability. HBoVS virus was detected in this patient’s BAL (Bronchoalveolar Lavage). This paper is reporting a rare case of probable HBoV meningitis. Abbreviations: CSF = cerebrospinal fluid , CRP = C-reactive protein, CT = computed tomography, HBoV = human bocavirus, HMPV = human metapneumovirus, PCR = polymerase chain reaction, RSV = respiratory syncytial virus

REFERENCES

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2) Schildgen O, Müller A, Allander T, Mackay IM, Völz S, Kupfer B, et al. Human bocavirus: passenger or pathogen in acute respiratory tract infections? ClinMicrobiol Rev. 2008; 21:291–304. doi:10.1128/ CMR.00030-07

3) Franz A, Adams O, Willems R, Bonzel L, Neuhausen N, SchweizerKrantz S, et al. Correlation of viral load of respiratory pathogens and co-infections with disease severity in children hospitalized for lower respiratory tract infection.

4) Deresinski S. Encephalitis and bocavirus? Clin Infect Dis. 2014;58: iii.

5) Akturk H, Sik G, Salman N, et al. Atypicalpresentation of human bocavirus: severe respiratory tract infection complicated with encephalopathy. J Med Virol. 2015.

6) Allander T, Tammi MT, Eriksson M, et al. Cloning of a human parvovirus by molecular screening of respiratory tract samples. Proc Natl Acad Sci USA. 2005; 102:12891–12896.

7) Mitui MT, Shahnawaz Bin Tabib SM, Matsumoto T, Khanam W, Ahmed S, Mori D, et al. Detection of human bocavirus in the cerebrospinal fluid of children with encephalitis. Clin Infect Dis. 2012; 54:964–7. http://dx.doi.org/10.1093/cid/cir957.

8) Human Bocavirus in Patients with Encephalitis, Sri Lanka, 2009–2010. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837659/

VOLUME 03 ISSUE 10 OCTOBER 2020

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