1Eddy Hartono
1Department of Obstetrics and Gynecology, Hasanuddin University, Makassar, South Sulawesi, Indonesia Elected International Society for Gynecological Endoscopy (ISGE) Board Member 2017-2021
ABSTRACT
Ovarian carcinoma was believed to had arised from fallopian tubes and then spread to ovarian surface and peritoneum. In addition, Lack of ovarian lesion precursor identified and the fact that bilateral salphingo-Oopherectomy performed to protect women with BRCA mutations from ovarian carcinoma lead many authors postulated that fallopian tube is probably the origin of serous ovarian carcinoma. Lately, initial form of serous carcinoma in fallopian tubes of women with BRCA mutation has been identified and this precursor lesion is known as STIC (serous tubal intraepitelial carcinoma).Prophylactic BSO in high risk women (with BRCA mutation) after completed parity may reduce risk of ovarian carcinoma dramatically (80%). Meanwhile, prophylactic salpingectomy as an alternative may suffice to prevent ovarian carcinoma if we could ensure that serous ovarian carcinoma arise from tubal fimbriae.
KEY-WORDSovarian carcinoma, BRCA, STIC, salpingo-Oopherectomy, salpingectomy
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VOLUME 02 ISSUE 02 NOVEMBER 2019
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